Domperidone Capsules are prescribed for providing relief from heartburn, acidity, & intestinal ulcers. They are formulated as combination of domperidone & rabeprazole, which belongs to proton pump inhibitor class and work by binding to H+/K+ ATPase pump to decrease acid production. These capsules get metabolized in liver by CYP3A4, CYP3A5, & CYP2C8 enzymes. They are known to have excellent protein binding ability of 92 to 96% with bioavailability or around 52%. Domperidone Capsules are absorbed by parietal cells of stomach and inhibit activity of acid producing pump by altering its configuration.